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The Peptide Journal

The science of prescription wellness.

Evidence-based writing on peptides, GLP-1 medicines, prescription skincare, and the future of care delivered at home — from our editorial team of clinicians and science writers.

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Peptides 101

Peptides 101: What They Are and Why Your Body Runs on Them

The building blocks behind hormones, healing, and metabolism — explained without the jargon.
Dr. Elena MarchettiJul 8, 2025
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Science & History

A Short History of Peptides: From Insulin to the Longevity Era

A century of discovery, from the first insulin injection to today's longevity research.
Marcus BellJul 17, 2025
Skincare

The Skin Barrier, Explained: Why Peptides Belong in Your Routine

How your skin's outer layer works — and where peptides fit in.
Dr. Priya AnandJul 29, 2025
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GLP-1

GLP-1 Explained: How Semaglutide Actually Works

The hormone pathway behind the most talked-about class of medicine in a decade.
Dr. Elena MarchettiAug 6, 2025
Skincare

Copper Peptides (GHK-Cu): The Skincare Ingredient Dermatologists Keep Talking About

What GHK-Cu is, what it does for skin, and what the evidence really shows.
Dr. Priya AnandAug 15, 2025
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Regulation

Compounded vs. Commercial: What a 503A Pharmacy Actually Does

Why compounding pharmacies exist, and how they're regulated.
Dr. Nathan ColeAug 26, 2025
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GLP-1

Semaglutide vs. Tirzepatide: A Head-to-Head for Metabolic Health

Two blockbuster molecules, one honest comparison of how they differ.
Dr. Elena MarchettiSep 4, 2025
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Performance

BPC-157 and the Science of Recovery Peptides

What we know — and don't yet know — about the popular recovery peptide.
Marcus BellSep 16, 2025
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GLP-1

Retatrutide: The 'Triple-G' Next-Generation GLP-1 to Watch

Why the next wave of metabolic medicine hits three receptors instead of one.
Dr. Elena MarchettiSep 25, 2025
Skincare

Tretinoin, Decoded: The Gold Standard of Prescription Skincare

Decades of evidence behind dermatology's most trusted anti-aging molecule.
Dr. Priya AnandOct 3, 2025
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Regulation

How the FDA Regulates Peptides and Compounded Medications

Approved, compounded, or off-limits — how the rules actually work.
Dr. Nathan ColeOct 14, 2025
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Performance

The 'Wolverine Stack': What People Mean and What the Science Says

Cutting through the internet hype around the popular recovery combo.
Marcus BellOct 23, 2025
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Performance

Peptides for Sleep and Recovery: What the Evidence Shows

How recovery, sleep quality, and peptide research intersect.
Marcus BellNov 5, 2025
Skincare

Melasma and Hyperpigmentation: A Prescription-First Approach

Why stubborn pigmentation often needs more than an over-the-counter serum.
Dr. Priya AnandNov 14, 2025
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GLP-1

GLP-1s Beyond Weight Loss: Metabolic, Cardiac, and Emerging Benefits

The expanding science of what GLP-1 medicines may do beyond the scale.
Dr. Elena MarchettiNov 25, 2025
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Safety

Understanding Peptide Safety: Sourcing, Dosing, and Why a Prescription Matters

The difference between a prescribed protocol and a gray-market gamble.
Dr. Nathan ColeDec 4, 2025
Skincare

Collagen, Elastin, and Peptides: The Anti-Aging Trio

How skin structure changes with age — and what actually helps.
Dr. Priya AnandDec 12, 2025
Longevity

The Longevity Movement: Where Peptides Fit In

Separating the durable science from the wellness hype.
Marcus BellDec 22, 2025
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GLP-1

New Year, New Metabolism: Setting Realistic GLP-1 Expectations

What healthy, sustainable progress on GLP-1 therapy actually looks like.
Dr. Elena MarchettiJan 8, 2026
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Performance

Ipamorelin and Growth-Hormone Secretagogues, Explained

A clear look at how these peptides signal the body — and the open questions.
Marcus BellJan 19, 2026
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Safety

Why 'Research Peptides' Sold Online Are a Red Flag

'Not for human consumption' means exactly what it says.
Dr. Nathan ColeJan 28, 2026
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How-To

The Telehealth Model: How Prescription Wellness Reaches Your Door

Intake to delivery — how modern prescription telehealth actually works.
Sofia ReyesFeb 5, 2026
Skincare

The Rise of Injectable and Topical Skin Peptides

Two very different delivery routes, and what each can realistically do.
Dr. Priya AnandFeb 16, 2026
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GLP-1

Tirzepatide Deep Dive: The Dual-Agonist Advantage

Why hitting two receptors changed the metabolic-medicine conversation.
Dr. Elena MarchettiFeb 25, 2026
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Performance

Muscle Preservation on GLP-1s: The Protein-and-Training Playbook

How to protect lean mass while losing fat on metabolic therapy.
Marcus BellMar 6, 2026
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Regulation

FDA Approvals Timeline: The Drugs That Defined the GLP-1 Era

From exenatide to today — the milestones that built a category.
Dr. Nathan ColeMar 17, 2026
Skincare

Niacinamide, Peptides, and Actives: Building a Dermatologist-Backed Routine

How to layer proven ingredients without overwhelming your skin.
Dr. Priya AnandMar 27, 2026
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GLP-1

Reta, Semaglutide, Tirzepatide: A Plain-English Comparison

Three generations of metabolic medicine, side by side.
Dr. Elena MarchettiApr 7, 2026
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Performance

Peptides for Joint and Tendon Health: Hype vs. Evidence

What the research supports, and where the marketing gets ahead of it.
Marcus BellApr 16, 2026
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Regulation

What 'Compounded GLP-1' Really Means After the Shortage

How the end of the shortage list reshaped access and compliance.
Dr. Nathan ColeApr 27, 2026
Longevity

The Gut-Skin Axis: Why Metabolic Health Shows on Your Face

The growing science connecting metabolism, inflammation, and skin.
Dr. Priya AnandMay 6, 2026
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GLP-1

Dosing, Titration, and Side Effects: A Patient's Guide to Starting GLP-1s

What to expect in the first weeks, and how titration protects you.
Dr. Elena MarchettiMay 15, 2026
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Safety

Peptide Myths, Busted: Separating Marketing From Medicine

The most common misconceptions, checked against the evidence.
Sofia ReyesMay 26, 2026
Longevity

Longevity Peptides: Epitalon, Thymosin, and the Research Frontier

A sober look at the peptides at the edge of longevity research.
Marcus BellJun 4, 2026
Skincare

Prescription Skincare vs. the Beauty Aisle: What You're Really Paying For

Where prescription strength matters — and where it doesn't.
Dr. Priya AnandJun 15, 2026
Longevity

The Future of Personalized Medicine: Peptides, Data, and Care at Home

Where at-home diagnostics, data, and prescription care are heading.
Dr. Elena MarchettiJun 26, 2026